Ileana Soto Reyes

Ileana Soto Reyes

Ileana Soto Reyes

Assistant Professor
Department of Biomedical & Translational Sciences
Department of Biological Sciences

Phone: 856-256-4500 x3585
Office: 201F Science Hall

Website: Soto Lab


  • BS, General Sciences, University of Puerto Rico
  • PhD, Biology, University of Puerto Rico
  • Postdoctoral, Johns Hopkins University, The Jackson Laboratory

Research Interests and Expertise:

  • Mechanisms of neurodegeneration
  • Neurovascular dysfunction in dementia
  • Neuroinflammatory responses in neurodegenerative diseases

Selected Publications:

  • Soto I, Grabowska WA, Onos KD, Graham LC, Jackson HM, Simeone SN, Howell GR (2016). Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease. Neurobiol Aging doi 10.16 (in press).
  • Graham LC, Harder JM, Soto I, de Vries WN, John SW, Howell GR (2016). Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease. Sci Rep. 2016 Feb 18;6:21568. doi: 10.1038/srep21568.
  • Soto I, Graham LC, Richter HJ, Radell JR, Grabowska W, Howell MC, Howell GR (2015). APOE stabilization by exercise prevents aging neurovascular dysfunction and complement induction. PLOS Bio, Oct 29, 13(10):e1002279.
  • Soto I, Howell GR, John CW, Kief JL, Libby RT and John SW (2014). DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation. PLOS One Sep 10;9(9):e107291
  • Howell GR, Soto I*, Ryan M, Graham LC, Smith RS, John SW (2013). Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice. J Neuroinflammation 10:76. *Co-first author.