James Grinias, Ph.D.
James Grinias, Ph.D.
James Grinias, Ph.D.
Professor
Contact Info
Biography
Websites:
Website
Research with Rowan
Faculty Profile
Education:
Post-Doctoral Associate, University of Michigen
Ph.D., Analytical Chemistry, University of North Carolina at Chapel Hill
B.S., Chemistry, Eastern Michigan University
Research Expertise:
Analytical Chemistry | Chromatography | Microfluidics
My research background focuses on the fundamental development of liquid chromatography (LC) columns in capillaries and microfluidic devices. LC columns are at the heart of many analytical separation techniques across pharmaceutical, environmental, and biomedical research projects. Early work focused on the physical structure of the packed chromatographic bed inside a fused silica capillary and led to strategies that could be used to pack more efficient columns in capillaries and also miniaturized microfluidic devices. Other interests have included understanding the physical processes beyond bed structure that impact column performance (included extra-column effects and frictional heating) and applying LC and mass spectrometry (MS) instrumentation to solve analytical problems in neuroscience and molecular physiology.
Honors and Awards:
The Analytical Scientist "Top 40 Under 40", 2018 and 2022
ACS Satinder Ahuja Award for Young Investigator in Separation Science, 2021
LCGC Emerging Leader Award, 2021
NSF CAREER Award, 2021
NIH MIRA Award, 2024
Professional Memberships:
American Chemical Society
Chromatography Forum of Delaware Valley
Selected Publications:
Xin, Y., Foster, S. W., Makey, D. M., Parker, D., Bradow, J., Wang, X., Berritt, S., Mongillo, R., Grinias, J. P., Kennedy, R. T. “Capillary LC Analysis of Reaction Mixtures at 4 s Intervals using a Droplet Microfluidic Injection”. Anal. Chem., 2024, 96(11), 4693-4701.
Saw, Y. L., Boughton, J. R., Wroniuk, F. L., Mostafa, M. E., Pelligrinelli, P. J., Calvez, S. A., Kaplitz, A. S., Perez, L. J., Edwards, J. E., Grinias, J. P. “Use of N-(4-aminophenyl)piperidine Derivatization to Improve Organic Acid Detection with Supercritical Fluid Chromatography-Mass Spectrometry”. J. Sep. Sci., 2023, 46(18), 2300343.
Foster, S. W., Parker, D., Piccolo, C., Will, M., Grinias, J. P. “Development of a Dual Electrospray Ionization Source with In-Line Absorbance-Based Voltage Control”. Anal. Bioanal. Chem., 2023, 415, 4147-4152.
Libert, B. P., Godinho, J. M., Foster, S. W., Grinias, J. P., Boyes, B. E. “Implementing 1.5 mm Internal Diameter Columns into Analytical Workflows”. J. Chromatogr. A, 2022, 1676, 463207.
Foster, S. W., Xie, X., Pham, M., Peaden, P. A., Patil, L. M., Tolley, L. T., Farnsworth, P. B., Tolley, H. D., Lee, M. L., Grinias, J. P. “Portable Capillary Liquid Chromatography for Pharmaceutical and Illicit Drug Analysis”. J. Sep. Sci., 2020, 43, 1623-1627.