Biography

Websites:
Website
Research with Rowan
Works

Education:
Post-Doctoral Associate, Princeton University
Ph.D., Organic Chemistry, Yale University
B.S., Chemistry, Long Island University

Research Expertise:
Chemical Biology | Organic Synthesis | Medicinal Chemistry

The goal of my research is to apply synthetic organic chemistry to enhance the understanding of biological processes. Applications of this general research focus include the study of bacterial quorum sensing, the development of new antibiotics, the selective detection of fatty acids and photoredox reaction development.

Professional Memberships:
American Chemical Society 
American Society of Microbiology 
Sigma Xi

Selected Publications:
Capilato, J.N.; Pellegrinelli, P.J.; Bernard, J.; Schnorbus, L.; Philippi, S.; Mattiucci, J.; Hoy, E.P.; Perez, L.J. 2021 ""Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives."" Organic & Biomolecular Chemistry, Jun 28;19(24):5298-5302. doi: 10.1039/d1ob00786f. Epub 2021 Jun 4. PMID: 34086029.

White B.; Sterrett J.D.; Grigoryan Z.; Lally L.; Heinze J.D.; Alikhan H.; Lowry C.A.; Perez L.J.; DeSipio J.; Phadtare S. 2021 “Characterization of gut microbiome and metabolome in Helicobacter pylori patients in an underprivileged community in the United States.” World J Gastroenterol. Sep 7;27(33):5575-5594. doi: 10.3748/wjg.v27.i33.5575. PMID: 34588753; PMCID: PMC8433610.

Watve S.; Barrasso K.; Jung S.A.; Davis K.J.; Hawver L.A.; Khataokar A.; Palaganas R.G.; Neiditch M.B.; Perez L.J.; Ng W.L. 2020 “Parallel quorum-sensing system in Vibrio cholerae prevents signal interference inside the host.” PLoS Pathog. Feb 14;16(2):e1008313. doi: 10.1371/journal.ppat.1008313. PMID: 32059031; PMCID: PMC7046293.

Flockton T.R.; Schnorbus L.; Araujo A.; Adams J.; Hammel M.; Perez L.J. 2019 “Inhibition of Pseudomonas aeruginosa Biofilm Formation with Surface Modified Polymeric Nanoparticles.” Pathogens. Apr 24;8(2):55. doi: 10.3390/pathogens8020055. PMID: 31022836; PMCID: PMC6631850.

Capilato, J.N.; Philippi, S.V.; Reardon,T.; McConnell, A.; Oliver, D.C.; Warren, A.; Adams, J.S.; Wu, C.; Perez. L.J. 2017 “Development of a Novel Series of Non-natural Triaryl Agonists and Antagonists of the Pseudomonas aeruginosa LasR Quorum Sensing Receptor” Bioorganic and Medicinal Chemistry, 25(1), 153-165. doi: 10.1016/j.bmc.2016.10.021. PubMed PMID: 27825554.